[HTML][HTML] Researching mitigation of alcohol binge drinking in polydrug abuse: KCNK13 and RASGRF2 Gene (s) Risk Polymorphisms Coupled with Genetic Addiction …

K Blum, MS Brodie, SC Pandey, JL Cadet… - Journal of Personalized …, 2022 - mdpi.com
… [25], is a leak potassium channel that stabilizes neurons and … cited genes modulate mesolimbic
dopaminergic neurons’ … has been shown to activate the cAMP-response element-binding …

Ion Channels and Metal Ions in Parkinson's Disease: Historical Perspective to the Current Scenario

B Vaidya, DS Padhy, HC Joshi, SS Sharma… - … : Method and Protocols, 2024 - Springer
Receptors of the D1 type couple to G s type of G-protein and function via activation of cAMP
signaling, while D2 receptors are coupled … , modulation of these potassium channels may be …

[HTML][HTML] Alzheimer's disease is an inherent, natural part of human brain aging: An integrated perspective

I Ferrer - Free Neuropathology, 2022 - ncbi.nlm.nih.gov
Alzheimer disease is one of the most challenging demons in our society due to its very high
prevalence and its clinical manifestations which cause deterioration of cognition, intelligence…

[HTML][HTML] GABAergic inhibitory interneuron deficits in Alzheimer's disease: implications for treatment

Y Xu, M Zhao, Y Han, H Zhang - Frontiers in neuroscience, 2020 - frontiersin.org
… inhibitor of GABA A receptor channel opening, indicating that … GABA B receptor R1 protein
(GABA B R1)-positive neurons … act as GABA B R1α ligands to modulate synaptic transmission, …

[HTML][HTML] Natural compounds as medical strategies in the prevention and treatment of psychiatric disorders seen in neurological diseases

E Küpeli Akkol, I Tatlı Çankaya… - Frontiers in …, 2021 - frontiersin.org
modulated acid-sensing ion channel currents resulting in increased cell viability. In MPTP-induced
PD in C57BL/6 mice, paeoniflorin reduced dopaminergic neuronalreceptor (Shahpiri …

A Comprehensive Study of miRNAs in Parkinson's Disease: Diagnostics and Therapeutic Approaches

S Owais, YH Siddique - … (Formerly Current Drug Targets-CNS & …, 2023 - ingentaconnect.com
… tain the proper functioning of the respiratory cell organelle [113]. … Overexpression of TFEB
modulates the ALP and is regulated … factor type 1 receptor (increased cellular cAMP), which is …

[PDF][PDF] Alzheimer's Disease & Treatment

XY Yeo, G Cunliffe, J Tang, J Gigg, L Zeng, S Jung - researchgate.net
… effects on neurons by modulating astrocyte activation and … due to their higher basal
mitochondrial respiration rate and lower … ), ascorbic acid and dpcAMP further enhance …

Protective microglial activation in Alzheimer's disease pathogenesis

PJ Paasila - 2021 - ses.library.usyd.edu.au
… The symptoms of AD reflect irreversible neuronal loss and … individuals with high
Alzheimer’s-type pathology. Poster … Therefore, therapeutic strategies aimed at modulating the …

The Key Elements and Overview of the Immune System

MM SalivaSaliva - Life Time: Your Body Clock and Its Essential …, 2022 - books.google.com
… There are also regulatory T-cells (also known as suppressor T-cells), which modulate the …
Positional syntenic cloning and functional characterization of the mammalian circadian …

[PDF][PDF] Unravelling the molecular basis of Alzheimer's disease and Frontotemporal dementia: genetic and epigenetic approach through Next Generation Sequencing …

F Sorrentino - air.unimi.it
… release through the activation of calcium channels [18,19]. APP … Tau is highly expressed in
neurons in the mammalian brain, … modulated by both genetic and environmental factors [233] …